QIAGEN OmicSoft and Biomedical Knowledge Base

Identifying critical drug-to-disease pathways using high-quality curated literature and omics data

87 views
January 23, 2025

In the drug discovery pipeline, evaluating multiple pathways between a drug target and disease is crucial for identifying potential therapeutic approaches. By examining overlapping pathways between competing drugs, researchers can uncover novel drug targets, while isoform-specific findings may elucidate unexpected clinical trial outcomes. Filtering these pathways with real-world expression and proteomics data is essential to validate new hypotheses and avoid pursuing non-viable leads.

Leveraging tools such as Neo4j, Python, and R, powered by curated databases like the QIAGEN Biomedical Knowledge Base and OmicSoft Lands, enables scientists to efficiently explore potential mechanisms of action during both target discovery and later stages of drug development.

Attendees will learn to:

• Apply pathfinding algorithms to navigate our comprehensive knowledge graph.

• Qualify drug candidates using curated scRNA-Seq expression data and detailed cell type annotations.

• Expand, filter, prioritize, and refine lists of biomarkers and drug targets through various advanced approaches.

Related videos

QIAGEN OmicSoft and Biomedical Knowledge Base

Knowledge graphs and more: Analytics-driven drug discovery using advanced biomedical...

1,983 views July 19, 2022

High-quality biomedical relationships knowledge is the cornerstone of modern...

QIAGEN OmicSoft and Biomedical Knowledge Base

Supercharge your AI in drug discovery with high-quality biomedical data

645 views October 11, 2023

If you’re working in pharma or biotech, you likely rely on artificial...

QIAGEN OmicSoft and Biomedical Knowledge Base

Unlocking the power of API-based 'omics queries

587 views June 12, 2023

If you're a data scientist or bioinformatician working in biopharma, here's...

QIAGEN OmicSoft and Biomedical Knowledge Base

Integrating deeply curated omics data with APIs for biomarkers and drug-target investigation

475 views September 19, 2023

If you’re a data scientist or bioinformatician working in biopharma and need...