QIAGEN OmicSoft and Biomedical Knowledge Base
Leveraging high-quality public proteomics data for biomarker and drug target investigation through OmicSoft Lands APIs
109 views
Using OmicSoft Lands APIs, you will learn how to:
• Easily locate proteomics samples and projects (studies) of interest (example can we locate proteomics data related to the breast cancer or specific drug treatment?)
• Check expression of a protein of interest (drug target or biomarkers) across different experimental groups or conditions (diseases, treatments, cell types and more) as well as across samples coming from different collections (example is a protein upregulated in breast cancer samples from TCGA and CPTAC but downregulated in normal samples from TCGA, GTEx and HPA)
• Correlate protein levels with RNA-seq expression data for the same samples, and compare differential expression results from proteomic and RNA-seq results
• Investigate whether there is correlation in expression between two (or a group/list of proteins) across different experimental groups/conditions (example do two proteins of interest show correlation in expression in TNBC samples? Is protein and gene expression correlated as well?)
• Derive a protein signature from conditions of interest (example are a group of protein upregulated in disease condition but downregulated upon drug treatment)
• Perform Geneset Enrichment for a group of proteins
Related videos
QIAGEN OmicSoft and Biomedical Knowledge Base
Knowledge graphs and more: Analytics-driven drug discovery using advanced biomedical...
High-quality biomedical relationships knowledge is the cornerstone of modern...
QIAGEN OmicSoft and Biomedical Knowledge Base
Supercharge your AI in drug discovery with high-quality biomedical data
If you’re working in pharma or biotech, you likely rely on artificial...
QIAGEN OmicSoft and Biomedical Knowledge Base
Unlocking the power of API-based 'omics queries
If you're a data scientist or bioinformatician working in biopharma, here's...
QIAGEN OmicSoft and Biomedical Knowledge Base
Integrating deeply curated omics data with APIs for biomarkers and drug-target investigation
If you’re a data scientist or bioinformatician working in biopharma and need...