QIAGEN IPA

Single Cell Analysis of the tumor microenvironmnet in High-grade Serous Ovarian Cancer (HGSOC)

60 views
November 03, 2022
Single-cell RNA sequencing (scRNA-seq) is an important technology that reveals gene expression differences between different cell types. Yet scRNA-seq data can be challenging to analyze and interpret. In this webinar, we’ll show how our QIAGEN Digital Insights bioinformatics tools can help you analyze and interpret whole transcriptome data from a human single-cell sequencing experiment.

We will analyze and compare the differentially expressed genes between stage III and normal for significant cell types in the tumor microenvironment from patient cases with HGSOC. We will use QIAGEN Ingenuity Pathway Analysis (IPA) to illuminate the underlying biology. We’ll show how IPA’s Land Explorer feature lets us compare and contextualize specific findings in HGSOC to other related or seemingly unrelated datasets.

In this webinar, you’ll learn how to:
Analyze scRNA-seq samples using QIAGEN CLC Genomic Workbench
Analyze and explore the biology of a processed dataset in QIAGEN IPA
Identify significant cell-specific canonical pathways or function-specific regulators
Generate hypotheses about novel regulatory networks that suggest drivers of the expression changes seen in the different cell types in stage III HGSOC
Visualize valuable information about a gene of interest in other contexts (disease, expression)
Compare gene signatures enriched in clusters of cells versus tens of thousands of gene expression signatures in QIAGEN IPA to pinpoint significant regulator genes associated with HGSOC stage III
Gain added insights about single-cell biology by comparing the HGSOC dataset in QIAGEN IPA to more than 118,000 public datasets which have been curated and processed in QIAGEN OmicSoft Suite

Related videos

QIAGEN IPA

QIAGEN Ingenuity Pathway Analysis (IPA) for grant writing and publications with new features

46 views October 20, 2022

QIAGEN Ingenuity Pathway Analysis (IPA) represents a robust resource to aid...

QIAGEN IPA

Multi omics analysis using QIAGEN Ingenuity Pathway Analysis

125 views October 20, 2022

In this 90-minute training session you’ll learn about how QIAGEN Ingenuity...

QIAGEN IPA

QIAGEN IPA Explorer Training: How to get the most from our virtual biobank of transcriptomic data

99 views September 15, 2022

Data generation and processing are costly and time-consuming. Work smarter,...

QIAGEN IPA

Extracting novel hypotheses and insights from single cell data

161 views May 20, 2022

Follow us on a journey of single cell data exploration. See how you can...