QIAGEN OmicSoft and Biomedical Knowledge Base

Public single cell RNA-seq data investigation using Omicsoft and Ingenuity Pathway Analysis

117 views
October 12, 2022
Slides from this training:
https://qiagen.showpad.com/share/qm9IZA718x6x5h6pfsiTa

Single cell lands tutorials: https://omicsoftdocs.github.io/ArraySuiteDoc/tutorials/SingleCellLand/Gene_Views/

Single cell RNA-sequencing (scRNA-seq) has been widely used to investigate tissue heterogeneity, identify novel cell types, study pathogenic mechanisms, development of targeted therapy (including immunotherapy) and more. Accordingly tremendous amount of scRNA-seq data has been deposited to public domains like GEO.

In this training, attendees will learn how to

· Locate public single cell studies of their interest using Omicsoft Single Cell Lands

· Study different cell types by dimension reduction plots (example t-SNE, UMAP)

· Investigate expression of genes of interest across different cell types (Violin plots, overlay expression on cluster)

· Identify key pathways and regulators from scRNA-seq data using Ingenuity Pathway Analysis

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