Good manufacturing practices (GMP) environments, such as biologics production facilities, require transparent, reproducible and audit-ready workflows. Here, we introduce a standardized short- or long-reads NGS-based workflow for viral detection using QIAGEN CLC Genomics Workbench Software, highlighting best practices to ensure sensitivity and specificity – and support reliable viral safety testing.

You will learn:

• To implement this new end-to-end NGS analysis workflow for viral detection using any sequencing technology

  • Process raw reads to final viral detection results using reproducible and traceable analysis steps, including quality control (QC), reference selection (e.g., RVDB) and contamination control

• How this new workflow aligns with GMP

  • See how CLC supports audit-ready analysis through full parameter tracking, versioned references and run documentation suitable for regulated environments

• To perform sensitive and robust viral detection

  • Detect low-level viral contamination using curated databases, optimized alignment strategies and result interpretation frameworks