QIAGEN CLC Genomics

HPV integration site mapping using QIAGEN CLC Genomics Workbench

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August 29, 2025

Join us for an in-depth walkthrough of HPV integration site mapping using the CLC Microbial Genomics Module. This webinar presents a rapid, automated workflow for identifying and visualizing viral integration sites (VIS) in the human genome, using data from HPV-positive cervical samples. By leveraging the Viral Hybrid Capture (VHC) and VIS Identification workflows, researchers can perform end-to-end analysis—from taxonomic profiling to pinpointing virus-host breakpoints. Learn how this streamlined pipeline enables high-resolution visualization, accurate integration mapping, and efficient reporting to advance our understanding of HPV-driven carcinogenesis.

Key Takeaways:

• End-to-End Automation: Explore how the CLC Genomics Workbench streamlines HPV integration analysis using the VHC and VIS workflows.

• Rapid Analysis: Achieve full sample processing in under 25 minutes with minimal manual input.

• Integrated Visualization Tools: Leverage auto-generated circular plots and genomic breakpoints for clear interpretation of virus-host interactions.

• Reference-Driven Accuracy: Built-in HPV and human genome references enhance precision and reduce runtime.

• Clinical Impact: Identify disrupted and neighboring host genes that may serve as biomarkers or therapeutic targets.

• Accessible & Scalable: Designed for non-programmers, the GUI-based platform supports diverse sample types and study sizes.

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