Three-dimensional (3D) cell culture structures like spheroids and organoids can be used to better understand complex diseases and deliver insights into potential theraputic opportunities. They are also complementary to two-dimensional (2D) cell cultures and in vivo models. These model systems offer scientists a detailed view of organ development, new insights on human development and disease, improving drug discovery and creating new approaches to precision medicine endeavors. Accordingly, this training will focus on using QIAGEN Ingenuity Pathway Analysis (IPA) and Omicsoft to study gene signatures in ‘omics data related to disease mechanisms and exploring drug action using organoid models.

During this 90-minute training, using Ingenuity Pathway Analysis/Omicsoft in combination with organoid data, attendees will learn how to:
• Quickly identify and study impacted pathways
• Establish biological mechanism underlying the diseases and drug treatments
• Easily compare datasets of interest with other user or public data pertaining to 2D cultures, 3D organoid cultures, in-vivo models or clinical studies to generate a strong hypothesis
• Export high quality graphical and tabular results

Speaker: Sumana Chintalapudi, Field Application Scientist, QIAGEN Digital Insights