Discovery and Research

From data to biological insight using QIAGEN CLC Single Cell Module and QIAGEN IPA: Single-cell sequencing of human fetal liver

179 views
June 11, 2021
Organ development during gestation is a complex series of hematopoietic events. Many different lineages are involved at various stages, from pluripotent hematopoietic progenitors to the final differentiated cell types. Analyzing the cellular and molecular mechanisms of liver development is key to understanding the cell types that comprise this vital organ and the roles they play. We analyzed single-cell transcriptomes of human fetal liver to highlight the different cell type clusters and their biology.

In this webinar, we will discuss how to:

Analyze the data from FASTQ files from single-cell RNA-seq (scRNA-seq) to produce differential expression profiles using QIAGEN CLC Single Cell Analysis Module and QIAGEN CLC Genomics Cloud Engine
Explore specific cellular markers to identify different cell types in human fetal human liver at various time points during gestation
Visualize valuable information regarding a specific marker gene of interest in other contexts (e.g., disease or expression)
Identify regulated canonical pathways and upstream regulators when comparing cell clusters using QIAGEN Ingenuity Pathway Analysis (IPA)
Generate hypotheses about novel regulatory networks that suggest drivers of observed expression changes in the different cell types during development
Gain additional insights about single-cell biology by comparing differential expression results from cell clusters in QIAGEN IPA to over 90,000 curated datasets

Related videos

Discovery and Research

RNA sequence analysis using PacBio and Illumina reads from a host-pathogen interaction - Part 3

121 views May 28, 2021

Learn ways to accelerate your agrigenomics research and analyses in this...

Discovery and Research

Exploring Single-Cell Transcriptomes Using Bioinformatics Solutions from QIAGEN - Part 2

1,262 views May 13, 2019

Cells – the basic building blocks of organisms – are each quite unique....

Discovery and Research

Assembly and annotation of plastid genomes using QIAGEN CLC Genomics - Part 2

119 views May 11, 2021

Learn ways to accelerate your agrigenomics research and analyses in this...

Discovery and Research

Transcriptomic analyses of in vitro flavivirus- or coronavirus-infected cell lines - Short

278 views August 20, 2020

The emergence of global viral infections reminds us of the significant public...