In this 90-minute training, attendees will learn how to call SNPs, MNPs and structural variants (insertions, deletions, inversions and copy number variants) using QIAGEN CLC Genomics Workbench. In addition, we will demonstrate how to annotate these variants using both QIAGEN CLC Genomics Workbench and QIAGEN Clinical Insight Interpret Translational (QCII-T).

In this training, we will discuss the following topics:
• Variant calling from FASTQ or BAM files using QIAGEN CLC Genomics Workbench
• Variant annotation using QIAGEN CLC Genomics Workbench and QCI-IT
• Filtering variants based on quality score, genetic analysis and biological context
• Identifying causal and actionable variants using the QIAGEN Knowledge Base (includes annotations from HGMD and COSMIC)
• Generating VCFs and tabular exports for further analysis in QIAGEN Ingenuity Pathway Analysis

Speaker: Sumana Chintalapudi, Ph.D., Field Application Scientist, QIAGEN Digital insights