Web seminar recordings
Clinical Metagenomics for Rapid Detection of Enteric Pathogens and Characterization of the Intestinal Microbiome
1,576 views
High-throughput sequencing, combined with high-resolution metagenomic analysis, provides a powerful diagnostic tool for clinical management of enteric disease. Forty-five patient samples of known and unknown disease etiology and 20 samples from health individuals were subjected to next-generation sequencing. Subsequent metagenomic analysis identified all microorganisms (bacteria, viruses, fungi and parasites) in the samples, including the expected pathogens in the samples of known etiology. Multiple pathogens were detected in the individual samples, providing evidence for polymicrobial infection. Patients were clearly differentiated from healthy individuals based on microorganism abundance and diversity. The speed, accuracy and actionable features of CosmosID bioinformatics and curated GenBook® databases, implemented in the QIAGEN Microbial Genomics Pro Suite, and the functional analysis, leveraging the QIAGEN functional metagenomics workflow, provide a powerful tool contributing to the revolution in clinical diagnostics, prophylactics and therapeutics that is now in progress globally.
Related videos
Web seminar recordings
Taxonomic profiling using shotgun metagenome data
In this webinar, we will introduce the latest workflows optimized for shotgun...
Web seminar recordings
Microbiome profiling from day one
Watch this webinar recording to learn how you can, with a few simple steps,...
Web seminar recordings
Whole genome sequencing for outbreak analysis and pathogen typing
With emphasis on outbreak prevention and control, this webinar walks...
Web seminar recordings
QIAGEN Clinical Insight (QCI) Interpret identifies targeted therapy and clinical trials in...
Hematological malignancies originating from hematopoietic and lymphoid tissue...