QIAGEN IPA

Discovery from public data (GEO, SRA and more) using Ingenuity Pathway Analysis

51 views
May 28, 2024
Per public demand, we are hosting a comprehensive training on how to effectively use sample-level public data and metadata from sources like GEO, SRA, TCGA, GTEx, Blueprint, CCLE and other sources through Ingenuity Pathway Analysis (IPA) and IPA Analysis Match Explorer feature. The trainer will walk through use cases in biomarker discovery, drug–target investigation, studying survival in custom patient cohorts, multi-gene correlation and more.

Note: The word “condition” below refers to different diseases, disease subtypes, treatments, cell types, cell lines and more.

This training will cover topics like
• How is a gene of interest expressed across different conditions?
• Is there a correlation in the expression of two genes or biomarkers of interest for a given condition?
• Can we derive a list of genes (for example, genes specific to a disease, treatment or cell type) for a given condition of interest?
• Can we generate custom cohorts of patients (for example, TP53 wt vs. mutant or PDCD1 high vs. low expression) and then generate survival curves representing those cohorts? Can we generate p-values to see if there is a significant difference?
• Can we detect the expression of a gene in different cell types from single-cell data?

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