tv.qiagenbioinformatics.com marketingbiox@qiagen.com https://tv.qiagenbioinformatics.com Watch tutorials, interviews and much more on our web based TV channel! en-us Visualplatform http://blogs.law.harvard.edu/tech/rss tv.qiagenbioinformatics.com CLC bio TV Watch tutorials, interviews and much more on our web based TV channel! clc bio tv, bioinformatics, genomics, research episodic no https://tv.qiagenbioinformatics.com/files/rv0.0/sitelogo.gif https://tv.qiagenbioinformatics.com http://tv.qiagenbioinformatics.com/photo/99492456/germline-and-somatic-variant <p>The accurate identification and annotation of germline and somatic variants rely on the accuracy and depth of reference databases containing information about the genetic variants, any associated phenotype and their clinical implications. By combining COSMIC, HGMD and QIAGEN QCI IT, scientists can annotate gene variants using the world’s most comprehensive and up-to-date curated scientific evidence and find biological connections in gene variants with manually curated scientific findings. The software and databases allow you to get valuable and reliable insights for your research project and speed up your discoveries related to disease-causing and disease-associated germline and somatic variants. <p>In this training, you will:</p> <p>1. Learn about the Catalogue of Somatic Mutations in Cancer (COSMIC), the world’s largest, most comprehensive, expert-curated resource for somatic mutations in human cancers, and how it can help you identify variants of interest for cancer research.<br> 2. Hear about the breadth and depth of the Human Gene Mutation Database (HGMD) and how it can aid in your search for disease-causing and disease-associated germline mutations.<br> 3. Explore the capabilities of QCI IT, which can help accelerate your discoveries from hereditary or tumor cohort analyses and find associations between gene variants and diseases from VCF files.</p></p><p><a href="http://tv.qiagenbioinformatics.com/photo/99492456/germline-and-somatic-variant"><img src="http://tv.qiagenbioinformatics.com/64968567/99492456/7d3df9d7d8cc1851030c431460e6ab80/standard/download-11-thumbnail.jpg" width="75" height=""/></a></p> http://tv.qiagenbioinformatics.com/photo/99492456 Thu, 02 May 2024 17:06:33 GMT Germline and Somatic Variant Investigation using COSMIC, HGMD and QCI-IT The accurate identification and annotation of germline and somatic variants rely on the accuracy and depth of reference databases containing information about the genetic variants, any associated phenotype and their clinical implications. By combining COSMIC, HGMD and QIAGEN QCI IT, scientists can annotate gene variants using the world’s most comprehensive and up-to-date curated scientific evidence and find biological connections in gene variants with manually curated scientific findings. The software and databases allow you to get valuable and reliable insights for your research project and speed up your discoveries related to disease-causing and disease-associated germline and somatic variants. In this training, you will: 1. Learn about the Catalogue of Somatic Mutations in Cancer (COSMIC), the world’s largest, most comprehensive, expert-curated resource for somatic mutations in human cancers, and how it can help you identify variants of interest for cancer research. 2. Hear about the breadth and depth of the Human Gene Mutation Database (HGMD) and how it can aid in your search for disease-causing and disease-associated germline mutations. 3. Explore the capabilities of QCI IT, which can help accelerate your discoveries from hereditary or tumor cohort analyses and find associations between gene variants and diseases from VCF files. The accurate identification and annotation of germline and somatic variants rely on the accuracy and depth of reference databases containing information about the genetic variants, any associated phenotype and their clinical implications. By... tv.qiagenbioinformatics.com 01:01:21 <p>The accurate identification and annotation of germline and somatic variants rely on the accuracy and depth of reference databases containing information about the genetic variants, any associated phenotype and their clinical implications. By combining COSMIC, HGMD and QIAGEN QCI IT, scientists can annotate gene variants using the world’s most comprehensive and up-to-date curated scientific evidence and find biological connections in gene variants with manually curated scientific findings. The software and databases allow you to get valuable and reliable insights for your research project and speed up your discoveries related to disease-causing and disease-associated germline and somatic variants. <p>In this training, you will:</p> <p>1. Learn about the Catalogue of Somatic Mutations in Cancer (COSMIC), the world’s largest, most comprehensive, expert-curated resource for somatic mutations in human cancers, and how it can help you identify variants of interest for cancer research.<br> 2. Hear about the breadth and depth of the Human Gene Mutation Database (HGMD) and how it can aid in your search for disease-causing and disease-associated germline mutations.<br> 3. Explore the capabilities of QCI IT, which can help accelerate your discoveries from hereditary or tumor cohort analyses and find associations between gene variants and diseases from VCF files.</p></p><p><a href="http://tv.qiagenbioinformatics.com/photo/99492456/germline-and-somatic-variant"><img src="http://tv.qiagenbioinformatics.com/64968567/99492456/7d3df9d7d8cc1851030c431460e6ab80/standard/download-11-thumbnail.jpg" width="75" height=""/></a></p> databases http://tv.qiagenbioinformatics.com/photo/71185915/access-to-real-world-data-and-2 <p>Across oncology applications, from research to molecular testing and pharmaceutical development, the ability to identify potentially actionable genetic alterations and exploit the molecular vulnerabilities of cancer is becoming increasingly difficult. Due to the sporadic nature of somatic cancers, the number of detected variants is exponentially growing, challenging scientists to confidently identify meaningful mutations that could influence or improve decisions in experimental design, at point-of-care, or in drug development. <p>In this webinar, we will introduce you to the Human Somatic Mutation Database (HSMD)—a new somatic database developed by QIAGEN that contains extensive genomic content relevant to solid tumors and hematological malignancies. Available as a web-based application, this expert-curated resource contains content from over 300,000 real-world clinical oncology cases combined with content from the QIAGEN Knowledge Base, providing gene-level, alteration-level, and disease-level information including clinically observed gene and variant frequencies across diseases. Users can easily search and explore mutational characteristics across genes, synthesize key findings from drug labels, clinical trials, and professional guidelines, and receive detailed annotations for each observed variant. In addition, users can interrogate a bibliography of over 150,000 variant specific PubMed articles and access individual summaries alteration-type specific information written by PhD scientists.</p> <p>In this webinar, you will learn:</p> <p>What content sources power HSMD<br> How to use and apply HSMD for multiple applications, including research, molecular testing, and pharmaceutical development<br> When and where you can access HSMD</p></p><p><a href="http://tv.qiagenbioinformatics.com/photo/71185915/access-to-real-world-data-and-2"><img src="http://tv.qiagenbioinformatics.com/64968569/71185915/60420a388e6ff40db3a94ebaf2f96685/standard/download-14-thumbnail.jpg" width="75" height=""/></a></p> http://tv.qiagenbioinformatics.com/photo/71185915 Wed, 20 Apr 2022 07:43:42 GMT Access to real-world data and 2 decades of expert curation Across oncology applications, from research to molecular testing and pharmaceutical development, the ability to identify potentially actionable genetic alterations and exploit the molecular vulnerabilities of cancer is becoming increasingly difficult. Due to the sporadic nature of somatic cancers, the number of detected variants is exponentially growing, challenging scientists to confidently identify meaningful mutations that could influence or improve decisions in experimental design, at point-of-care, or in drug development. In this webinar, we will introduce you to the Human Somatic Mutation Database (HSMD)—a new somatic database developed by QIAGEN that contains extensive genomic content relevant to solid tumors and hematological malignancies. Available as a web-based application, this expert-curated resource contains content from over 300,000 real-world clinical oncology cases combined with content from the QIAGEN Knowledge Base, providing gene-level, alteration-level, and disease-level information including clinically observed gene and variant frequencies across diseases. Users can easily search and explore mutational characteristics across genes, synthesize key findings from drug labels, clinical trials, and professional guidelines, and receive detailed annotations for each observed variant. In addition, users can interrogate a bibliography of over 150,000 variant specific PubMed articles and access individual summaries alteration-type specific information written by PhD scientists. In this webinar, you will learn: What content sources power HSMD How to use and apply HSMD for multiple applications, including research, molecular testing, and pharmaceutical development When and where you can access HSMD Across oncology applications, from research to molecular testing and pharmaceutical development, the ability to identify potentially actionable genetic alterations and exploit the molecular vulnerabilities of cancer is becoming increasingly... tv.qiagenbioinformatics.com 44:12 <p>Across oncology applications, from research to molecular testing and pharmaceutical development, the ability to identify potentially actionable genetic alterations and exploit the molecular vulnerabilities of cancer is becoming increasingly difficult. Due to the sporadic nature of somatic cancers, the number of detected variants is exponentially growing, challenging scientists to confidently identify meaningful mutations that could influence or improve decisions in experimental design, at point-of-care, or in drug development. <p>In this webinar, we will introduce you to the Human Somatic Mutation Database (HSMD)—a new somatic database developed by QIAGEN that contains extensive genomic content relevant to solid tumors and hematological malignancies. Available as a web-based application, this expert-curated resource contains content from over 300,000 real-world clinical oncology cases combined with content from the QIAGEN Knowledge Base, providing gene-level, alteration-level, and disease-level information including clinically observed gene and variant frequencies across diseases. Users can easily search and explore mutational characteristics across genes, synthesize key findings from drug labels, clinical trials, and professional guidelines, and receive detailed annotations for each observed variant. In addition, users can interrogate a bibliography of over 150,000 variant specific PubMed articles and access individual summaries alteration-type specific information written by PhD scientists.</p> <p>In this webinar, you will learn:</p> <p>What content sources power HSMD<br> How to use and apply HSMD for multiple applications, including research, molecular testing, and pharmaceutical development<br> When and where you can access HSMD</p></p><p><a href="http://tv.qiagenbioinformatics.com/photo/71185915/access-to-real-world-data-and-2"><img src="http://tv.qiagenbioinformatics.com/64968569/71185915/60420a388e6ff40db3a94ebaf2f96685/standard/download-14-thumbnail.jpg" width="75" height=""/></a></p> databases HSMD oncology Somatic database