QCI I Translational

Investigating genomic variants using QIAGEN CLC Genomics Workbench, QCI...

Thu, 08 Jan 2026 10:40:11 GMT

Discovery of new genes implicated in hereditary diseases or cancer progression is challenging and advancing rapidly with an increase in the amount of cohort data to analyze from next generation sequencing (NGS) data to associations between gene variants and diseases, and finally to biological mechanisms of these gene variants. Combining QIAGEN CLC Genomics Workbench, QCII-T, and IPA, scientists can analyze sequencing data obtained from a variety of NGS technologies, annotate gene variants using the world’s most comprehensive and up-to-date curated scientific evidence, and find biological connections in gene variants with manually curated scientific findings. Get valuable and reliable insights for your research project and speed up your discoveries by using a streamlined NGS analysis workflow.

In this webinar, attendees will have the opportunity to:

1. Learn how to import whole genome or exome sequencing data into QIAGEN CLC Genomics Workbench and use the ultra-fast LightSpeed Module that delivers end-to-end NGS FASTQ to VCF pipeline;

2. Explore capabilities in QCII-T which can enable scientists to accelerate discoveries from hereditary or tumor cohort analyses to find associations between gene variants and diseases;

3. Learn how to use IPA and its manually curated content among other integrated scientific evidence to uncover novel biological mechanisms underlying these gene variants.

QCI Interpret Translational Tutorial

Fri, 03 Oct 2025 19:44:38 GMT

From Variants to Vision: Driving Oncology Breakthroughs in Translational...

Thu, 26 Jun 2025 22:44:33 GMT

Aptly called "bench-to-bedside", translational research involves developing and testing new techniques and therapies for better disease management and patient care. This field plays a pivotal role in ensuring that discoveries realize their potential for real-world impact instead of staying confined to the lab.

Join us in exploring how two tools can accelerate translational cancer research. Human Somatic Mutation Database (HSMD) Professional is an expert-curated somatic knowledgebase that incorporates real-world cancer patient data, while QCI Interpret Translational (QCI-IT) is a variant annotation and interpretation tool that provides automated ACMG/AMP classification, phenotype-specific insights and more.

You’ll learn how:

• HSMD, which includes data from over 870K real-world oncology cases, provides easily accessible and reliable data for the identification of clinically significant and actionable mutations

• QCI-IT can process uploaded variant data to prioritize impacting symptoms, pathways and genes implicated in drug response or disease progression

• HSMD and QCI-IT can be used in tandem to efficiently transition from exploratory insights to actionable decisions

Simplify gene discovery Three solutions to decode variants and pathways

Mon, 03 Mar 2025 22:13:15 GMT

Does your lab need a faster and easier way to uncover associations between gene variants, diseases, and biological pathways? As next-generation sequencing (NGS) data grows exponentially, discovering new genes implicated in hereditary diseases or cancer progression has never been more challenging or time-intensive. However, advanced bioinformatics tools and expert-curated content from QIAGEN can simplify, enrich, and accelerate your research.

Join us for an informative webinar that will provide a deep-dive into three cutting-edge solutions: QIAGEN CLC Genomics Workbench, QCI Interpret Translational, and QIAGEN Ingenuity Pathway Analysis (IPA). Attendees will learn through demonstrations how these three solutions can analyze sequencing data from a variety of NGS technologies, annotate genes using the world’s most comprehensive and up-to-date curated scientific evidence, and find biological connections in gene variants. Helping you streamline your NGS workflows from FASTQ to discovery, these three easy-to-use solutions will enable you to pinpoint disease-associated variants, uncover biological mechanisms, and turn data into breakthroughs faster than ever.

In this webinar, you’ll learn how to:

• Use the LightSpeed module of QIAGEN CLC Genomics Workbench for ultra-fast, FASTQ-to-VCF NGS data processing that can deliver whole genome or exome results in minutes.

• Leverage QCI Interpret Translational to accelerate your understanding of hereditary and tumor variants with powerful cohort analysis capabilities.

• Use QIAGEN IPA to uncover novel biological mechanisms with the world’s most comprehensive manually curated database.

This is your opportunity to speed up discoveries, gain deeper insights, and make impactful connections. Don’t miss out—your next breakthrough starts here.

Germline and Somatic Variant Investigation using COSMIC, HGMD and QCI-IT

Thu, 02 May 2024 17:06:33 GMT

The accurate identification and annotation of germline and somatic variants rely on the accuracy and depth of reference databases containing information about the genetic variants, any associated phenotype and their clinical implications. By combining COSMIC, HGMD and QIAGEN QCI IT, scientists can annotate gene variants using the world’s most comprehensive and up-to-date curated scientific evidence and find biological connections in gene variants with manually curated scientific findings. The software and databases allow you to get valuable and reliable insights for your research project and speed up your discoveries related to disease-causing and disease-associated germline and somatic variants.

In this training, you will:

1. Learn about the Catalogue of Somatic Mutations in Cancer (COSMIC), the world’s largest, most comprehensive, expert-curated resource for somatic mutations in human cancers, and how it can help you identify variants of interest for cancer research.
2. Hear about the breadth and depth of the Human Gene Mutation Database (HGMD) and how it can aid in your search for disease-causing and disease-associated germline mutations.
3. Explore the capabilities of QCI IT, which can help accelerate your discoveries from hereditary or tumor cohort analyses and find associations between gene variants and diseases from VCF files.

Investigating genomic variants using QIAGEN CLC Genomics Workbench, QCI...

Fri, 21 Jul 2023 15:27:54 GMT

Discovering new genes implicated in hereditary diseases or cancer progression is challenging yet advancing rapidly due to the increase in next-generation sequencing (NGS) cohort data. These data analyses produce insights into associations between gene variants and diseases and the biological mechanisms of these gene variants.

By combining QIAGEN CLC Genomics Workbench, QCII-T and QIAGEN IPA, you can analyze sequencing data obtained from a variety of NGS technologies, annotate gene variants using the world’s most comprehensive and up-to-date curated scientific evidence and find biological connections in gene variants with manually curated scientific findings. Using a streamlined NGS analysis workflow, you’ll get valuable and reliable insights for your research project and speed up your discoveries.

In this training, you’ll:
1. Learn to import whole genome or exosome sequencing data into QIAGEN CLC Genomics Workbench and use the ultra-fast LightSpeed Module that delivers an end-to-end NGS FASTQ to VCF pipeline
2. Explore the capabilities in QCII-T which can help accelerate your discoveries from hereditary or tumor cohort analyses to find associations between gene variants and diseases
3. Learn how to use QIAGEN IPA and its manually curated content, among other integrated scientific evidence, to uncover novel biological mechanisms underlying these gene variants

Take your genome research to the next level with QCI Interpret Translational

Fri, 03 Feb 2023 04:39:38 GMT

Discovery of new genes implicated in hereditary diseases or cancer progression is challenging and advancing rapidly with an increase in the amount of cohort data to analyze. It is estimated that every day one new gene is discovered to be associated with a disease. QCI Interpret Translational can get your research to the next level by providing you all the necessary analysis tools with the world’s most comprehensive and up-to-date curated scientific evidence. Get valuable and reliable insights for your research project and speed up your discoveries by using a streamlined NGS analysis workflow in a user-friendly interface without needing bioinformatics expertise.

In this webinar, viewers will have the opportunity to:

Explore capabilities which can enable them to accelerate discoveries from hereditary or tumor cohort analyses
Discover interactive tools with current and comprehensive associations between gene variants and diseases
Learn how these resources are supported by unique curated content among other integrated scientific evidence

Variant Calling to Biological Insights – A Lynch Syndrome Case Study

Thu, 09 Dec 2021 07:19:18 GMT

In this webinar, we present a case study on Lynch syndrome (LS), a hereditary condition characterized by a high risk of colorectal cancer, endometrial cancer, and other neoplasia that typically manifests in the context of germline variants in DNA mismatched genes.
To study whether other germline pathogenic variants of hereditary cancer genes are present in patients previously diagnosed with LS, the researchers analyzed a comprehensive panel of cancer-predisposing genes by NGS among 84 LS probands.

With this study as an example, we will illustrate how you can use your own data and public data to conduct translational research using 3 software solutions from QIAGEN.

This webinar will focus on the following elements:

Data analysis – How you can efficiently retrieve and process FASTQ data with accurate variant interpretation using CLC Genomics Workbench
Interpretation – How you can take a set of variants and rapidly assess sample variants for disease relevance and pathogenicity using QCI Interpret Translational
Discovery – How you can combine results and contextualize variant biomarkers with other public datasets using QIAGEN Ingenuity Pathway Analysis (IPA)

Speaker:

Eric Seiser, PhD
Senior Field Applications Scientist
QIAGEN Digital Insights