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Using OmicSoft OncoLand to integrate public expression
QIAGEN OmicSoft Lands are high-quality curated repositories of genomics and proteomics data sourced from public, published studies (GEO, EBI, SRA) and consortia (TCGA, CPTAC, GTEx, and more). Because of our expert curation and stringent quality checks, OmicSoft users can deeply investigate across diverse oncology and normal tissue/cell datasets to discover and validate candidate drug targets and biomarkers.
In this training, attendees will use OmicSoft Studio, our graphical user interface, to access public data from The Cancer Genome Atlas (TCGA). Using this data, you will learn how to:
• View gene expression and somatic mutation frequency across different tumor types and conditions
• Identify genes whose expression correlates or anti-correlates with mutation of your target
• Prioritize your candidate biomarkers using expression data across comparisons (tumor vs. normal, MUT vs. WT, etc.)
• Establish survival consequences from changes in your candidate biomarker’s expression or mutation status
01:32:56 minutes