Case Stories

Dr. John Martignetti comments on RNA research

Wed, 12 Apr 2017 09:11:09 GMT

For years, RNA research lagged behind investigations of DNA. Now, a growing understanding of RNA’s vital role in regulating normal physiology is attracting increasing interest - revealing a powerful driver of both disease and health.

Identifying rare disease variants

Tue, 10 Jan 2017 09:48:26 GMT

Dr. Rump, PhD, head of Molecular Genetics Group at the Institute for Clinical Genomics in Dresden, uses Biomedical Genomics Workbench to compare exomes in rare and inherited diseases, and to identify the cause of the disease. With increasing amounts of variant and annotation data, the right informatics tools and techniques are indispensable for Dr. Rump and his team, allowing them to not only create the data via NGS but also to explore it and formulate new ideas.

Clinical genomic sequencing: Where we’ve been, where we are, and where we’re...

Mon, 07 Nov 2016 13:46:59 GMT

Presented by Dr. Josh Deignan, Ph.D., F.A.C.M.G.

Transcriptome analysis of Kupffer cells after uptake of pancreatic cancer exomes

Mon, 30 May 2016 14:47:10 GMT

Presented by Principal Scientist, Dr. Jean-Noel Billaud, at AACR 2016

Targeted RNA sequencing, Urban Metagenomics, and Astronaut Genomics

Tue, 10 May 2016 19:27:00 GMT

Dr. Chris Mason’s presentation covers the QIAseq Targeted RNA Panel beta testing, QIAGEN’s Sample-to-Insight solution for Metagenomics sequencing as demonstrated in the Metasub project, as well as Chris latest endeavor the, “Twins Study”, which will be a comprehensive genomic study of the impact of spaceflight on the human body. Astronaut Scott Kelly will be studied during the course of his year-long stay at the ISS as will his twin brother, Mark Kelly, a former NASA astronaut who will remain on earth.

Center for Genomic Medicine, Rigshospitalet - The Phase 1 project

Thu, 19 May 2016 10:19:43 GMT

Finn Cilius Nielsen and Lars Jønson at Center for Genomic Medicine work closely with the Phase I Unit, looking to decide whether deep sequencing of tumors will provide data that can be used for treatment of patients and improve their survival in the long run.

Unraveling the genomic complexity of common and rare genetic disorders

Tue, 31 May 2016 14:13:33 GMT

Unraveling the genomic complexity of common and rare genetic disorders: NGS bioinformatics for the discovery of causal variants in sensorineural hereditary hearing loss and various rare conditions
Presented by Rajini R. Haraksingh, Ph.D., Postdoctoral fellow, Stanford University and Vice Precident, Rare Genomics Institute

April 16, 2015

King Cobra Project

Mon, 13 Aug 2012 20:43:21 GMT

Ron Dirks from ZF-screens elaborates on the King Cobra project, in collaboration with BaseClear.

Population adaptive divergence studies on whitefish in Canada

Mon, 10 Sep 2012 17:00:39 GMT

Dr. Louis Bernatchez from IBIS, Laval University, elaborates on their projects.

Pubertal onset research

Mon, 11 Nov 2013 13:35:11 GMT

A recent project at Rigshospitalet is correlating longitudinal clinical measurements to sequence data.

Non-profit development of disease-resistant cassava for farmers in Africa

Tue, 05 Jun 2012 18:03:10 GMT

Dr. Claude M. Fauquet elaborates on how the not-for-profit Donald Danforth Plant Science Center in St. Louis, is mixing science and technology to improve agricultural production of cassava to make a difference for millions of people in Africa.

Cystic fibrosis research at IBIS, Laval University

Tue, 10 Jul 2012 10:56:39 GMT

Dr. Roger C. Lévesque from IBIS, Laval University in Quebec City, elaborates on their cystic fibrosis and lung cancer research.

Glaucoma Research in Japan

Tue, 12 Feb 2013 08:02:48 GMT

Dr. Tashiro from Kyoto Medical University elucidates the molecular mechanisms of Glaucoma. He works towards identifying the pathogenesis of the eye disease together with his team.

Colon cancer project

Thu, 11 Apr 2013 07:55:29 GMT

Prof. Sun from the National Cheng Kung University College of Medicine in Taiwan shares how she handles large amounts of data while working towards making new discoveries.

XSQ support

Wed, 11 Dec 2013 08:58:54 GMT

Prof. Robert Donnelly and his staff at Rutgers use the 5500 SOLiD system for large-scale sequencing projects, and they save a lot of time being able to import the SOLiD XSQ files directly into CLC Genomics Workbench.

Genome sequencing of human pathogens

Tue, 12 Mar 2013 08:01:46 GMT

By sequencing important bacterial pathogen genomes, Dr. Chiu, from Chang Gung Children's Hospital in Taiwan, hopes to provide new knowledge to the medical community.

Computational resources for NGS research at University of Pittsburgh

Tue, 11 Dec 2012 11:06:52 GMT

The University of Pittsburgh and UPMC use informatics and computing infrastructure for clinical high-throughput sequencing.

Center for Genomic Medicine - Rigshospitalet

Mon, 25 Apr 2016 13:28:51 GMT

Center for Genomic Medicine works closely with the Phase I Unit, looking to decide whether deep sequencing of tumors will provide data that can be used for treatment of patients and improve their survival in the long run.

The Rubber Genome Project - Sequencing of the white blood of the world economy

Thu, 15 Mar 2012 09:54:34 GMT

Rubber Genome, white blood, Draft Genome Publication, Malaysia, Centre for Chemical Biology, Dr. Alam

JCVI: Drive your science forward

Tue, 18 Oct 2011 13:10:57 GMT

JCVI focus on new cutting edge tools giving them the advantage to drive the science forward

Interview with Indresh Singh, Lead, Informatics Core Service, JCVI:
"Analysis is the bottleneck. Analysis costs and disk storage costs is going up, so the only solution is to analyze the data faster."

FABI investigating the genome of a fungus causing the pitch canker disease

Thu, 08 Sep 2011 08:44:03 GMT

Interview with Dr. Martin Coetzee, Senior Lecturer, Department of Genetics and Researcher at Forestry and Agricultural Biotechnology Institute (FABI) and Dr. Arshad Ismail, GS Technology Platform Manager, Inqaba Biotec.

Investigating ancestral polyploidy in plants at Penn State

Tue, 16 Aug 2011 09:39:38 GMT

Interview with Dr. Claude dePamphilis, Professor of Biology at Penn State University.

ARC establishes South African bioinformatics network for agricultural research

Thu, 12 May 2011 09:37:18 GMT

Interview with Dr. Jasper Rees, Head of the Biotechnology Platform, Agricultural Research Council (ARC), South Africa

In order to address their key strategic areas of improving food security, increasing crop productivity, Agricultural Research Council recently made two large investments.

The first in a complete High-Throughput Sequencing platform solution allowing them to incorporate both NGS and advanced genotyping technologies into a single instrument.

The second investment was made in the area of bioinformatics – hardware and software. The core of this investment sits with an enterprise platform enabling them to effiently distribute genomics tools and bioinformatics analysis throughout the ARC – spread accross nearly 2000 km of geographical space.

Using RNAi to regulate gene expression in cancer and TTR

Tue, 08 Feb 2011 12:09:41 GMT

Head of Informatics, Greg Hinkle, PhD, Alnylam Pharmaceuticals elaborates on the potential of RNAi, including examples in liver cancer, and TTR.

Use your valuable bioinformatics staff for breaking new grounds

Thu, 09 Dec 2010 10:58:28 GMT

Associate Director at ICBR, University of Florida, Dr. Bill Farmerie, says today's challenge is not dealing with the instruments themselves, but the data that comes off them.

RNA-Seq milk cell transcriptome research at UC Davis

Tue, 09 Nov 2010 12:26:40 GMT

At present UC Davis are working on improving the content of oligosaccharides in bovine milk.
Working on an initiative referred to as the Foods for Health Institute, whose goal is to improve human health through food.

See Professor Juan F. Medrano, PhD from the Animal Genomics Laboratory, UC Davis elaborate on their exciting project.

Science as a Service by EdgeBio

Mon, 30 Aug 2010 11:30:46 GMT

Director of Bioinformatics at EdgeBio, Justin H. Johnson, elaborates on the concept of Science as a Service at CHI's "Beyond Sequencing" conference in San Francisco, June 2010.

Double haploid apple genome project in South Africa

Thu, 17 Jun 2010 22:27:52 GMT

Professor Jasper Rees and Dr. Joseph Mafofo from the University of the Western Cape, South Africa, shares some preliminary results and challenges from their Golden Delicious apple genome sequencing project.

Genome project - Research on plant diseases

Thu, 17 Jun 2010 18:15:06 GMT

See how CLC bio's de novo assembler is making research easier for Eva Stukenbrock, Postdoc, Cand. Scient. PhD at BiRC, Aarhus University

Lupus erythematosus research by OMRF

Thu, 17 Jun 2010 15:28:01 GMT

Researchers at the Oklahoma Medical Research Foundation elaborate on their sequence capture approach to identifying novel genes that are linked to Lupus erythematosus.

X-Linked mental retardation study from the Max-Planck Institute

Thu, 17 Jun 2010 10:01:15 GMT

Scientist, Jeremy Lambert, from RainDance elaborates on how their microdroplet technology, high-throughput sequencing, and CLC bio’s bioinformatics tools can be used in resequencing projects to effectively speed up the process of analyzing complex diseases. In this video examplified by a publication on X-Linked mental retardation from the Max-Planck Institute.